PET/MRI brain scans for understanding depression
Part of Mental health clinical trials.
This trial uses two special brain scans (DPA-714 and FDG PET/MRI) to look at inflammation and brain activity in people with first-episode or recurrent depression, and in healthy volunteers. It aims to find brain differences that could lead to better treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 35 and 85 years old if you have recurrent depression, or a similar age as those patients if it is your first episode.
- You have not had any alcohol, coffee, or other psychoactive substances in the 24 hours before the scan.
- You score at least 24 on the MMSE memory test and 26 on the MOCA thinking test.
- You have not taken any anti-infective medicine in the past month or had a cold or fever in the past 2 weeks.
- You are willing to sign a consent form and can complete the required questionnaires.
- You do not have any MRI contraindications (like metal implants) or serious medical conditions (like heart, liver, or kidney disease).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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