Nerve stimulation for Parkinson's and essential tremor
Part of Brain & nervous system clinical trials.
This study tests a non-invasive nerve stimulation device for reducing tremors in people with Parkinson's disease or essential tremor. It follows up participants from a previous trial to see if benefits last up to 24 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have already completed the earlier TS004-PD study.
- You have stable medications for at least 30 days before starting.
- For Parkinson's: you have some slowness or stiffness and a tremor in your hand or arm, even during your best medication periods.
- For essential tremor: you have a visible hand, arm, foot, or leg tremor.
- You do not have an implanted device like a pacemaker, deep brain stimulator, or defibrillator.
- You are not pregnant, breastfeeding, or planning to become pregnant, and you use reliable birth control if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing whether a device that gently stimulates the nerves in your arm (called non-invasive neuromodulation) can safely reduce hand tremors over a long period. It might help with activities like eating, writing, or dressing.
This trial tests whether gentle electrical stimulation to the skin (called sensory electrical stimulation) can help reduce resting tremors in people with Parkinson's disease. Resting tremors are shaking that happens when your muscles are relaxed, like when your hands are in your lap.
This trial tests whether a non-invasive brain stimulation method called Temporal Interference can help reduce tremors in people with essential tremor. It may offer a new way to calm hand shaking without surgery or medication.
This trial tests a new, non-invasive brain stimulation technique called transcranial temporal interference stimulation (tTIS) to see if it can reduce tremors in people with essential tremor. It is for people who are already candidates for a surgical treatment called MRI-guided focused ultrasound thalamotomy.
This trial tests a new type of brain stimulation called closed-loop TMS that automatically adjusts to help reduce tremor in people with Parkinson's disease or essential tremor. The goal is to see if this technology can better control shaking than standard treatments.
This study tests whether ultrasound waves applied to a part of the brain (the cerebellum) can safely affect brain activity. It involves healthy volunteers and people with essential tremor, a condition causing shaky hands, to see if this approach might help.
Hear when a new Essential Tremor trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.