Clinical trials
Essential Tremor clinical trials
Below are recruiting essential tremor clinical trials, each written for real people, not researchers. We’re tracking 60 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07428447Recruiting
Skin test to predict Parkinson's risk in essential tremor
This study uses a skin biopsy to check for a protein linked to Parkinson's disease. It aims to see if people with essential tremor who have this protein are more likely to develop Parkinson's disease.
Scottsdale, ArizonaAges 50–85 - NCT06635811Recruiting
Circadian-adjusted deep brain stimulation for essential tremor
This study tests whether adjusting the timing of your deep brain stimulation (DBS) based on your body's natural daily rhythms can better control essential tremor. If you have a Medtronic Percept DBS device, you may be able to join.
Gainesville, FloridaAges 21–89 - NCT04212780Recruiting
Testing a smarter DBS system for severe essential tremor
This trial tests an upgraded deep brain stimulation (DBS) system that can “sense” tremor and adjust treatment in a loop. It’s designed for people with severe essential tremor whose tremor is still disabling despite standard DBS and medication.
Gainesville, FloridaAges 21–99 - NCT05897775RecruitingPhase 1
Testing a new deep brain stimulator approach for essential tremor
This Phase 1 study tests a coordinated reset deep brain stimulation program for people with essential tremor. It may help reduce tremor symptoms using a specific implanted brain-stimulation device, along with special high-strength MRI and CT imaging before and after surgery.
Minneapolis, MinnesotaAges 21 years+ - NCT05909839Recruiting
7-Tesla brain MRI network study for deep brain stimulation tremor
This study looks at detailed brain imaging using a very strong MRI (7-Tesla) to understand brain network changes after deep brain stimulation for essential tremor. It may help improve how DBS works and how tremor can be better treated in the future.
Amsterdam, North HollandAges 18 years+ - NCT06145932Recruiting
Repetitive TMS for essential tremor
This trial tests whether repetitive transcranial magnetic stimulation (TMS) — a non-invasive treatment that uses magnetic pulses to calm overactive brain cells — can help reduce shaking in people with essential tremor. If you have essential tremor and no metal implants or other brain conditions, you may be eligible to participate.
SuzhouAges 18–80 - NCT06293638Recruiting
Brain changes during deep brain stimulation for essential tremor
This study looks at how deep brain stimulation (DBS) affects brain networks in people with essential tremor (ET). The goal is to understand the brain changes that happen during DBS treatment, which may help improve the therapy.
Cleveland, OhioAges 30–80 - NCT06331052Recruiting
Focused Ultrasound for Essential Tremor
This trial tests a focused ultrasound treatment for essential tremor that uses MRI to guide sound waves to stop the shaking. It might help if other treatments haven't worked well enough.
Chapel Hill, North CarolinaAges 22 years+ - NCT06610877Recruiting
Ultrasound treatment for essential tremor
This trial tests if a focused ultrasound treatment can help people with essential tremor that hasn't improved with medication. It is designed for those already scheduled for a similar procedure using MRI guidance.
San Francisco, CaliforniaAges 18 years+ - NCT06821906RecruitingPhase 2
Stereotactic radiosurgery for essential tremor
This trial tests a precise type of radiation therapy (stereotactic radiosurgery) to treat essential tremor when medications don't work well enough. It aims to reduce shaking without the need for brain surgery.
GliwiceAges 50 years+ - NCT07016425Recruiting
Testing a new brain stimulation for essential tremor
This trial tests whether a non-invasive brain stimulation method called Temporal Interference can help reduce tremors in people with essential tremor. It may offer a new way to calm hand shaking without surgery or medication.
Beijing, Beijing MunicipalityAges 30–70 - NCT07066358Recruiting
Treating essential tremor with focused heat to both sides of the brain
This trial tests a one-time procedure that uses heat to stop the brain cells causing tremor. It might help people with severe shaking that hasn't improved with medication.
Shinjuku-Ku, TokyoAges 20–70 - NCT07074002RecruitingPhase 2
Study of a new drug for essential tremor
This trial tests a new study drug (BP1.4979) to see if it can reduce shaking in people with essential tremor. It's for people who have had arm tremors for at least 3 years and have not had surgery for tremor.
AmiensAges 18–85 - NCT07212244Recruiting
Focused ultrasound for hard-to-treat tremor
This study uses a focused ultrasound treatment guided by MRI to calm hand tremors in people with essential tremor that hasn't responded to medication. It aims to improve daily life by reducing shaking without the need for surgery.
Toronto, OntarioAges 22 years+ - NCT07344194RecruitingPhase 1/Phase 2
Magnetic brain stimulation for essential tremor
This study tests a new type of magnetic brain stimulation (given as pulses to two brain areas) to help reduce shaking from essential tremor. It is for people whose tremor hasn't improved enough with standard medications.
São Paulo, São PauloAges 18 years+ - NCT01734122Recruiting
Focused radiation for essential or Parkinson tremor
This trial tests whether precisely targeted radiation to the brain can reduce tremors in people whose symptoms are not controlled enough by medication. It may help those who prefer radiation over deep brain surgery options.
Nashville, TennesseeAges 18 years+ - NCT07599592RecruitingEarly Phase 1
Ultrasound Treatment for Essential Tremor
This early-stage study tests whether focused ultrasound waves can safely reduce hand tremors in people with essential tremor. The ultrasound is applied from outside the skin without surgery, and researchers want to see if it helps calm unwanted shaking.
Los Angeles, CaliforniaAges 18–90 - NCT06676501Enrolling by invitation
Second side focused ultrasound for essential tremor
This study tests whether a second focused ultrasound treatment on the other side of the brain can safely and effectively reduce tremor in people with essential tremor who already had one treatment. It's for those whose tremor is not well controlled by medication or previous treatments.
BeijingAges 22 years+ - NCT06349538Enrolling by invitation
Essential tremor subtypes and progression markers study
This study looks for biological markers to better understand different types of essential tremor and how the condition changes over time. It may help identify who has which subtype and predict disease progression.
Graz, AustriaAges 18 years+ - NCT04032470Recruiting
Deep brain stimulation registry for essential tremor patients
This study collects information from adults with essential tremor who are getting deep brain stimulation under the hospital’s standard safety guidelines. It may help improve how this treatment is chosen and used for people with tremor over time.
InnsbruckAges 18 years+ - NCT05976074Enrolling by invitation
Wearable device study for people with essential tremor
This study tests a wearable device and a phone app to better track daily-life symptoms in people with essential tremor. It may help researchers understand how tremor changes during everyday tasks using video and audio recordings.
Rochester, MinnesotaAges 18 years+ - NCT07673107RecruitingPhase 2
Botulinum toxin injection for essential tremor of hands and arms
This trial tests an investigational botulinum toxin injection (AGN-151607-DP) to reduce shaking in the hands and arms caused by essential tremor. It is for adults who have been diagnosed with this condition and who do not have certain nerve or muscle disorders.
Fresno, CaliforniaAges 18–85 - NCT03832712Recruiting
Study for adults with essential tremor not helped by beta blockers
This trial looks at people with essential tremor (a shaking condition) whose usual medicine—beta blockers—didn’t work well or couldn’t be tolerated. The goal is to test a treatment approach that may improve tremor control and daily function.
GothenburgAges 18–75 - NCT06570421Recruiting
Nerve stimulation for Parkinson's and essential tremor
This study tests a non-invasive nerve stimulation device for reducing tremors in people with Parkinson's disease or essential tremor. It follows up participants from a previous trial to see if benefits last up to 24 months.
OstravaAges 18 years+
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Essential Tremor trials by city
Studies with a site in or near these metro areas.
Essential Tremor trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for essential tremor?
- Yes. Clin2 currently lists 60 recruiting essential tremor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a essential tremor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a essential tremor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.