Clin2
NCT06574568Possibly a fitRecruiting

Study of YKST02 for relapsed or refractory multiple myeloma

Relapsed or Refractory Multiple Myeloma

Treatments studied

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This study tests a new drug called YKST02 for people with multiple myeloma that has come back or hasn't responded to other treatments. The goal is to see if it can help when other therapies have stopped working.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
70 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have been diagnosed with multiple myeloma and have tried at least two different types of myeloma treatments (like immunomodulatory drugs, proteasome inhibitors, or anti-CD38 drugs).
  • Your myeloma is still active and measurable (for example, a certain level of M-protein in blood or urine).
  • You are able to take care of yourself (ECOG score 0–1) and are expected to live at least 12 more weeks.
  • You have not had a prior treatment that targets BCMA (like CAR-T or a bispecific antibody).
  • You do not have serious heart problems, uncontrolled infections, or other major medical conditions that would make the trial unsafe.
  • You are willing to use effective contraception if you are of childbearing age.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05565807Recruiting· Phase 1/Phase 2
Study drug for difficult myeloma after prior treatments

This trial tests an anti-CD38 antibody drug that is “linked” to a cancer-killing payload (an antibody-drug conjugate) in people with multiple myeloma that has returned or did not respond to standard treatments. It is mainly looking at safety first, and also whether it can reduce myeloma in heavily pre-treated patients.

Beijing, Beijing Municipality
NCT06232096Recruiting· Phase 1/Phase 2
Study of MBS314 for relapsed or refractory multiple myeloma

This trial tests a new drug called MBS314 for people whose multiple myeloma has returned or stopped responding to other treatments. The goal is to see if MBS314 can help shrink or control the myeloma.

Beijing
NCT07681596Recruiting· Phase 1/Phase 2
Study of a new drug for relapsed or refractory multiple myeloma

This trial tests an experimental drug for multiple myeloma that has come back or not responded to at least three previous treatments. It aims to see if the drug can help people whose cancer has progressed despite prior therapies including a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 antibody.

Duarte, California
NCT07695740Not yet recruiting· Phase 2
Study of YKST02 for multiple myeloma that has come back or not responded

This trial tests an investigational drug called YKST02 for people with multiple myeloma that has returned or not improved after at least two prior treatments. The goal is to see if YKST02 can help control the cancer.

Beijing, Beijing Municipality
NCT07726160Not yet recruiting· Phase 1
Study of KIV-318 for advanced multiple myeloma

This trial tests an investigational drug called KIV-318 for people with multiple myeloma that has come back or not responded to standard treatments. It aims to see if KIV-318 is safe and effective in targeting a protein called BCMA on myeloma cells.

Tianjin, China
NCT07652281Recruiting· Phase 1
Study of SHR-5421 for multiple myeloma

This trial tests a new drug, SHR-5421, for people with multiple myeloma that has come back or stopped responding to treatment. It aims to see if the drug is safe and how well it works.

Beijing, Beijing Municipality

Hear when a new Relapsed or Refractory Multiple Myeloma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.