Clin2
NCT06576583Possibly a fitRecruiting

Cartilage graft for kneecap arthritis

Patellofemoral Osteoarthritis

Part of Bones, joints & muscles clinical trials.

This trial tests a new graft made from lab-grown cartilage to treat knee pain under the kneecap. It compares the graft to standard surgery for people with moderate-to-severe kneecap arthritis who haven't improved with other treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
150 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old.
  • You have osteoarthritis (wear-and-tear) specifically under the kneecap (patellofemoral joint).
  • You have tried other treatments, like physical therapy or pain creams, but they didn't work well enough.
  • You have not had any major knee surgery in the past year.
  • Your knee must bend at least 125 degrees and straighten fully (or within 5 degrees of straight).
  • You are generally healthy, with no active infections, bleeding disorders, or conditions that would make surgery risky.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06163573Recruiting· Phase 2
Engineered cartilage for kneecap arthritis

This trial tests a new way to treat arthritis in the kneecap area using specially grown cartilage. If you have kneecap pain and haven't been helped by other treatments, this might be an option to discuss with your doctor.

Zagreb
NCT06423300Recruiting
Testing a new implant for kneecap cartilage damage

This trial tests a new implant called the Patellar LIFT System to treat pain caused by cartilage damage behind the kneecap. It is for people who have tried other treatments like physical therapy but still have significant knee pain.

La Mesa, California
NCT04937998Recruiting
PRP or hyaluronic acid injections for knee cartilage pain

This trial compares two injection treatments—platelet-rich plasma (PRP) and hyaluronic acid (HA)—for pain from osteoarthritis in the kneecap area. It looks to see which injection works better and for whom, using symptom follow-up and imaging.

Bologna
NCT06400862Recruiting· Phase 1
Treating knee cartilage damage with lab-grown bone marrow tissue

This trial tests a new treatment that uses your own bone marrow cells to grow a piece of tissue to repair damaged knee cartilage. It's for people with a single, medium-sized cartilage injury on the thigh bone part of the knee joint that hasn't gotten better with other treatments.

Jordon
NCT06895889Not yet recruiting· Phase 1/Phase 2
New cartilage repair implant for knee damage

This study tests a new implant made from your own cells to repair damaged knee cartilage. It aims to reduce pain and improve knee function by replacing the damaged area with a living implant.

NCT07249489Not yet recruiting
Knee cartilage repair implant study

This study tests a new implant designed to help repair damaged knee cartilage. It may help people with knee pain or injury by encouraging new cartilage to grow.

Vancouver, British Columbia

Hear when a new Patellofemoral Osteoarthritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.