Can a supplement prevent mouth sores during chemo?
Part of Cancer, Digestive system, Mouth & dental clinical trials.
This trial tests whether a special supplement (synbiotic) can prevent mouth sores caused by chemotherapy in people with colorectal cancer. It's for those starting treatment who live in or near Belo Horizonte, Brazil.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have colorectal cancer and are about to start your first chemotherapy treatment.
- You are 18 years or older.
- You are getting chemo with capecitabine (with or without oxaliplatin) plus radiation therapy.
- You do not have a colostomy, or you have one in the transverse, descending, or sigmoid part of the colon.
- You live in Belo Horizonte or the surrounding metropolitan area.
- You have not taken antibiotics, antifungals, probiotics, or antidiarrheal medication in the last 15 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a supplement called alpha-lipoic acid (ALA) can protect against painful mouth sores caused by chemotherapy (FOLFOX-6) in people with colorectal cancer. If you are starting FOLFOX-6 for the first time for colorectal cancer, this study may help reduce treatment side effects.
This study tests whether taking a probiotic (a beneficial bacteria) called Clostridium butyricum can help reduce side effects during chemotherapy after colorectal cancer surgery.
This trial tests if using a steroid mouthwash can prevent painful mouth sores caused by certain chemotherapy drugs. It aims to help patients who are starting or already receiving chemotherapy known to cause mouth sores.
This trial studies whether taking a daily probiotic supplement can reduce the nerve damage (neuropathy) that often happens with oxaliplatin chemotherapy. If it works, it might help you feel better and stay on your full chemo plan.
This trial tests whether a special probiotic supplement (good bacteria) can reduce belly discomfort caused by abemaciclib, a hormone therapy drug for early breast cancer. You would take the supplement alongside your cancer treatment to see if it helps with stomach side effects.
This study tests whether taking a probiotic supplement during chemotherapy can help people with stage III colon cancer. It aims to see if it improves treatment outcomes or reduces side effects.
Hear when a new Colo-rectal Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.