Clin2
NCT06576986Possibly a fitRecruiting

Can a supplement prevent mouth sores during chemo?

Colo-rectal Cancer

Part of Cancer, Digestive system, Mouth & dental clinical trials.

This trial tests whether a special supplement (synbiotic) can prevent mouth sores caused by chemotherapy in people with colorectal cancer. It's for those starting treatment who live in or near Belo Horizonte, Brazil.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
80 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have colorectal cancer and are about to start your first chemotherapy treatment.
  • You are 18 years or older.
  • You are getting chemo with capecitabine (with or without oxaliplatin) plus radiation therapy.
  • You do not have a colostomy, or you have one in the transverse, descending, or sigmoid part of the colon.
  • You live in Belo Horizonte or the surrounding metropolitan area.
  • You have not taken antibiotics, antifungals, probiotics, or antidiarrheal medication in the last 15 days.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07736495Recruiting· Phase 2/Phase 3
Alpha-lipoic acid for chemo mouth sores in colorectal cancer

This trial tests if a supplement called alpha-lipoic acid (ALA) can protect against painful mouth sores caused by chemotherapy (FOLFOX-6) in people with colorectal cancer. If you are starting FOLFOX-6 for the first time for colorectal cancer, this study may help reduce treatment side effects.

Cairo
NCT07152886Not yet recruiting· Phase 4
Can a probiotic help with chemo side effects in colorectal cancer?

This trial tests whether taking a probiotic called Clostridium butyricum can reduce side effects during chemotherapy after colorectal cancer surgery. It's for people who have had their tumor removed and are about to start adjuvant treatment.

Qingdao, Shandong
NCT07179094Not yet recruiting
Peppermint oil mouthwash to prevent mouth sores during chemo

This trial tests if a peppermint oil mouthwash can help prevent painful mouth sores caused by chemotherapy. It is for adults with blood cancers who are about to get strong or moderate chemotherapy that often causes nausea and vomiting.

NCT07287826Recruiting· Phase 4
Steroid mouthwash to prevent mouth sores during chemo

This trial tests if using a steroid mouthwash can prevent painful mouth sores caused by certain chemotherapy drugs. It aims to help patients who are starting or already receiving chemotherapy known to cause mouth sores.

Baton Rouge, Louisiana
NCT07073092Not yet recruiting· Phase 2
Propolis to prevent mouth sores from chemo in kids

This trial tests whether a natural bee product called propolis can prevent painful mouth sores caused by strong chemotherapy in children with cancer. If you are a child getting intensive chemo and have a healthy mouth now, you may be able to join.

Cairo
NCT07733817Not yet recruiting
Probiotics to prevent nerve damage from colon cancer chemo

This trial tests whether taking probiotics can reduce nerve damage (peripheral neuropathy) caused by oxaliplatin chemotherapy in people with stage III colon cancer. If you are starting chemo soon, this study may help protect your nerves.

Caen, Centre François Baclesse

Hear when a new Colo-rectal Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.