Probiotics to reduce nerve damage from colon cancer chemo
Part of Brain & nervous system, Cancer, Digestive system, Pain clinical trials.
This trial studies whether taking a daily probiotic supplement can reduce the nerve damage (neuropathy) that often happens with oxaliplatin chemotherapy. If it works, it might help you feel better and stay on your full chemo plan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have stage III colon cancer that was surgically removed.
- Your doctor plans to start you on chemotherapy with oxaliplatin (called FOLFOX or XELOX).
- You are in good enough health to be active and care for yourself (ECOG score 0 or 1).
- You agree to provide stool and blood samples for research.
- Your blood test results must meet certain levels of blood cells, liver, and kidney function.
- You must be willing to use contraception if you could become pregnant.
- You can understand French and are covered by a social security system.
- You must not have any nerve damage from other causes, not have taken probiotics or antibiotics recently, and not have other serious health conditions that would interfere.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether acupuncture can relieve the nerve pain and tingling in the hands and feet that often occurs after treatment with oxaliplatin, a chemotherapy drug for gastrointestinal cancers. The study aims to help people manage this side effect and improve their daily comfort.
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This trial is testing two medications (memantine and rosuvastatin) that may protect your nerves from damage during chemotherapy. It is for people with stage III or IV colorectal cancer who are about to start a specific chemo regimen (FOLFOX or XELOX).
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