Pregnenolone for PTSD and alcohol use in veterans
Part of Mental health clinical trials.
This study tests an investigational drug (pregnenolone) to see if it can help veterans who have both PTSD and alcohol use disorder. The goal is to find the right dose that might reduce stress-related drinking.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 21 and 70 years old and have served in the U.S. military (either active duty or in the past).
- You need a current diagnosis of alcohol use disorder (mild, moderate, or severe) and must be drinking at a level that is above the weekly limits (more than 14 drinks for men or 7 for women per week).
- You need to have significant PTSD symptoms, as measured by a standard questionnaire.
- You cannot be taking certain medications that affect alcohol use (like naltrexone or topiramate) within 30 days of starting.
- If you are a woman who can become pregnant, you must agree to use an effective birth control method during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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