Study of brexanolone for PTSD and alcohol use in veterans
Part of Mental health clinical trials.
This trial tests if a drug called brexanolone can help veterans with both PTSD and alcohol use disorder. You will be asked about your drinking and PTSD symptoms, and may receive the drug in a lab setting.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a veteran or active-duty military, age 21 to 70.
- You have been diagnosed with alcohol use disorder (even mild) in the past 6 months and currently drink more than 14 drinks per week (men) or 7 drinks per week (women), with heavy drinking days at least once a week.
- You have PTSD symptoms that cause you distress, as measured by a doctor's interview and a questionnaire.
- You are not taking medications like naltrexone, topiramate, or gabapentin for alcohol use within the past 30 days.
- You are not currently in trauma-focused therapy for PTSD (like cognitive processing therapy or prolonged exposure) and have not been for at least 2 weeks before starting the study.
- You are willing to not try to quit drinking completely during the study (you must still drink alcohol before lab sessions).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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