Comparing two antipsychotic medications for acute schizophrenia
Treatments studied
Part of Mental health clinical trials.
This study tests whether a new medication, cariprazine, works as well as an older one, aripiprazole, for people having a recent episode of schizophrenia. Participants will receive one of the two drugs for a set period, and the study will track how well symptoms improve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with schizophrenia and are currently having an acute episode (symptoms like delusions, hallucinations, or disorganized thinking).
- Your symptom score is within a certain range, and your overall condition is moderately severe or worse.
- Your body mass index (BMI) is between 18 and 40.
- You have not been hospitalized for this episode for more than 21 days.
- You have not tried two different antipsychotic medications at adequate doses for at least 6 weeks without success.
- You have not used long-acting antipsychotic injections within the last 6 months, and you have not taken more than 15 mg of aripiprazole within the last 14 days.
- You do not have certain heart conditions, brain disorders, or uncontrolled diabetes, and your liver and kidney function are within normal limits.
- You are not pregnant or breastfeeding, and you agree to use contraception if needed.
- You are willing to comply with study visits and medication schedules.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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