Lithium or cariprazine for bipolar depression
Treatments studied
Part of Mental health clinical trials.
This trial compares lithium versus cariprazine to treat an episode of depression in people with bipolar disorder. It may help find which medicine works better and is safer during the acute (active) phase of depression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have bipolar disorder type 1 or type 2 and you are currently in a depressive episode
- Your depression is moderate to severe (at least a 21 score on the Major Depression Inventory you report yourself)
- You are 18 to 64 years old at the time of randomization (starting the study assignment)
- In the last 2 weeks, you have not started or increased medicines for mood/mental health (except some sleep/anxiety medicines like benzodiazepines, zopiclone, zolpidem, or melatonin)
- In the last 4 weeks, you have not started formal talk therapy sessions (psychoeducation is allowed)
- You can understand Danish and can take part safely (including not having severe confusion/dementia or current psychotic symptoms)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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