Testing antibiotics through a brain drain for hard-to-treat infections
Treatments studied
Part of Infections clinical trials.
This trial is for adults with a serious brain infection caused by drug-resistant bacteria. It tests giving an antibiotic (polymyxin B) directly into the brain through a drain tube to see if it works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a brain infection that did not get better with at least 5 days of IV polymyxin B.
- You have a drain tube (EVD) in your head to remove fluid.
- Lab tests show the bacteria in your spinal fluid are resistant to many drugs but sensitive to polymyxin B.
- You do not have a severe allergy to polymyxin B.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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