Antibiotics for serious bacterial meningitis
Treatments studied
Part of Brain & nervous system, Infections clinical trials.
This trial tests giving antibiotics both through a small hole in the skull and through a vein to treat serious bacterial meningitis that has not improved with standard care. It aims to see if this combined approach is more effective in fighting the infection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with moderate to severe bacterial meningitis.
- Your symptoms have not improved or have worsened after 48-72 hours of standard antibiotics.
- You may need treatment with specific strong antibiotics (polymyxin B, tigecycline, or vancomycin).
- You have not had antibiotics injected directly into the spinal fluid before this trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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