Clin2
NCT06605651Possibly a fitNot yet recruiting

Phage therapy for knee or hip joint infections caused by staph bacteria

Hip Prosthesis InfectionKnee Prosthesis Infection

Treatments studied

Part of Bones, joints & muscles, Infections clinical trials.

This trial tests a new treatment using viruses that attack bacteria (called phages) to fight infections in knee or hip replacements caused by Staphylococcus aureus. It may help people who still have the infection after a surgery to clean the joint, called DAIR.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have an infection in your hip or knee replacement caused by a bacteria called Staphylococcus aureus (staph).
  • You are scheduled to have or recently had a procedure to clean the joint (called DAIR).
  • You are not currently in severe sepsis or septic shock, and your health is generally stable.
  • You are willing to use effective birth control during the study if you or your partner can have children.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07698002Not yet recruiting· Phase 2/Phase 3
Phage therapy and antibiotics for joint infections

This study tests whether adding a treatment with special viruses (called phages) to standard antibiotic care can help clear a joint infection more effectively after surgery. The goal is to improve your chances of keeping the artificial hip or knee and avoid the need for more procedures.

Ottawa
NCT06798168AVAILABLE
Phage therapy for drug-resistant joint infections

This trial studies a treatment using viruses that attack bacteria (called phages) to fight a stubborn joint infection that hasn't improved with other treatments. It may help people with chronic infections that resist antibiotics.

Ottawa
NCT07461337Not yet recruiting· Phase 1/Phase 2
Bacteriophage therapy for stubborn joint infections

This trial tests a treatment using viruses that attack bacteria to fight a chronic infection in a joint replacement. It might help people whose joint infection has not cleared up with standard antibiotics or surgery.

Calgary
NCT06942624Not yet recruiting· Phase 1/Phase 2
Phage therapy for a long-term joint replacement infection

This trial tests a special treatment using viruses (called phages) that target and kill the bacteria causing a long-term joint replacement infection. It's designed for people who have tried many other treatments without success.

Winnipeg, Manitoba
NCT07214311Recruiting· Phase 2/Phase 3
Preventing repeat knee infection after joint-saving surgery

This trial tests a new medicine called PLG0206 to help prevent a knee infection from coming back after a procedure to clean the joint while keeping the artificial knee in place. If you qualify, you'll receive the study medicine or a placebo along with standard antibiotics.

Sarasota, Florida
NCT06468163Not yet recruiting
Antibiotic injection for knee infection after surgery

This trial tests whether giving antibiotics directly into the knee through a small tube can help clear an infection that develops after a knee replacement surgery. It aims to improve the success of a procedure called DAIR, which is used to treat early knee joint infections.

Hear when a new Hip Prosthesis Infection trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.