Phage therapy for staph infections in hip or knee replacements
Treatments studied
Part of Bones, joints & muscles, Infections, Injuries & trauma clinical trials.
This study tests a treatment using viruses (phages) that kill staph bacteria in people with an infected hip or knee replacement. The treatment is given after a surgery to clean the joint, and the goal is to see if it's safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a staph infection in your hip or knee replacement, confirmed by your doctor.
- You are scheduled for a surgery called DAIR to clean the joint.
- You are not severely ill or in septic shock.
- You have a life expectancy of at least one year.
- You agree to use effective birth control if you or your partner can become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a new treatment using viruses (phages) that target specific bacteria. If you have a hip or knee joint infection caused by a single type of bacteria (Staph aureus or Pseudomonas) and are having a surgery to clean the joint, this trial may be an option for you.
This trial tests a virus-based treatment (bacteriophage) for a chronic joint infection caused by a specific bacteria that hasn't responded to other treatments.
This trial tests a virus-based treatment for a chronic hip or knee implant infection caused by a hard-to-treat bacteria. It is designed as a single-patient study that may help when standard treatments have failed.
This trial tests whether specially designed viruses (bacteriophages) can treat infections around orthopedic implants like joint replacements or bone hardware. Bacteriophages are natural virus-like particles that attack bacteria, and this study evaluates whether they are safe and effective when given to patients with hard-to-treat implant infections.
This study tests whether adding the antibiotic rifampicin to standard treatment works better than standard treatment alone for staph infections in hip or knee replacements. The goal is to find a more effective way to clear the infection and avoid more surgeries.
This study checks the safety of using phage therapy (viruses that target certain bacteria) in adults being treated for serious infections. If you meet the safety rules, your care team may enroll you to help confirm phage treatment is safe.
Hear when a new Hip Prosthesis Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.