Adjuvant adebrelimab and capecitabine for high-risk bile duct cancer
Treatments studied
Part of Cancer clinical trials.
This trial is for people with bile duct cancer who have had surgery to remove all visible cancer but are at high risk of it coming back. It tests whether adding two medications — adebrelimab (an immunotherapy) and capecitabine (a chemotherapy pill) — after surgery can help prevent the cancer from returning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your bile duct cancer was surgically removed with no visible cancer left behind and you have certain high-risk features (like a large tumor or spread to lymph nodes).
- You have not had any other cancer treatment before your surgery.
- You are between 18 and 75 years old and generally active (able to do daily tasks).
- Your blood tests and organ function meet specific safety levels.
- You do not have an autoimmune disease, active tuberculosis, or active hepatitis B or C.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests adding the immunotherapy adebrelimab to standard chemotherapy (gemcitabine and nab-paclitaxel) as a first treatment for advanced biliary tract cancer that can't be removed by surgery. The goal is to see if this combination helps shrink tumors and improve outcomes.
This trial is testing whether a new drug (SHR-8068) combined with adebrelimab and chemotherapy works better than the current standard treatment for people with advanced bile duct cancer who have not been treated yet.
This trial tests a combination of chemotherapy directly into the liver artery, an immunotherapy drug, and a targeted therapy pill before surgery for a type of bile duct cancer that has a high chance of coming back. The goal is to see if this approach can improve outcomes for patients whose cancer is still removable but has certain high-risk features.
This trial tests a combination of chemotherapy, immunotherapy (adebrelimab), and a targeted therapy (apatinib) before and after surgery for bile duct cancer that can be removed and has a high risk of coming back. It aims to see if this approach can lower the chance of recurrence.
This trial tests a combination of an immunotherapy (adebrelimab), a targeted therapy (apatinib), and two chemotherapy drugs (gemcitabine and cisplatin) given before surgery for biliary tract cancers that are removable but at high risk of coming back. The goal is to see if this approach helps shrink the tumor and improve outcomes after surgery.
This trial tests a new combination of two targeted drugs (Recaticimab and Adebrelimab) plus chemotherapy for people with advanced bile duct or gallbladder cancer that cannot be removed by surgery. The goal is to see if this approach can shrink tumors or slow the disease.
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