Comparing two surgical methods for jaw bone problem
Part of Bones, joints & muscles, Mouth & dental clinical trials.
This trial compares two surgical techniques for treating medication-related jaw bone problems (MRONJ): one using a special vibrating tool (piezoelectric) and the other using conventional tools. It aims to see which approach leads to better healing and fewer complications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have been diagnosed with stage 1 or stage 2 MRONJ (a bone problem in the jaw linked to certain medications).
- Your doctor has decided that surgery is needed for your condition.
- You have not had radiation therapy to your head or neck area.
- You have not had surgery for this same jaw problem before.
- You are able to attend all follow-up visits as scheduled.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how a specific jaw problem (osteonecrosis) may happen in people taking bone-strengthening medications. It aims to better understand and manage this side effect.
This trial tests whether using a special blood product (leukocyte- and platelet-rich fibrin, or L-PRF) during surgery for a jawbone condition called MRONJ helps improve healing. Patients who need surgery under general anesthesia for advanced MRONJ may be able to join.
This study follows patients with medication-related osteonecrosis of the jaw (a bone condition often caused by certain cancer or osteoporosis medicines) using imaging scans to understand how the bone changes over time. The goal is to better predict outcomes and improve treatment.
This study looks at what changes happen in the jawbone in people with osteonecrosis of the jaw (a damaged jawbone area), whether or not they take certain cancer/bone medicines. It may help doctors better understand the condition and how it behaves over time.
This trial tests a new digital method for planning jaw surgery that uses virtual guides instead of traditional splints. It may help make surgery more precise and reduce discomfort.
This trial compares a new, gentler surgical tool called piezosurgery (which uses ultrasound vibrations) with standard tools for jaw repositioning surgery. It aims to see if piezosurgery causes less damage to nearby tissues and speeds up recovery.
Hear when a new Osteonecrosis of the Jaw trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.