Treating jaw bone problems around dental implants: keep or remove?
Part of Bones, joints & muscles, Hormones & metabolism clinical trials.
This study compares two ways to treat a jaw bone problem caused by medications (called MRONJ) when it happens around a dental implant. One option is to keep the implant and treat the bone, the other is to remove the implant. The goal is to see which approach leads to better healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with medication-related osteonecrosis of the jaw (MRONJ), which is a bone problem in the jaw caused by certain medications.
- This bone problem is around a dental implant (a false tooth root placed in your jawbone).
- X-rays show that the bone loss around the implant is between 20% and 60% of the implant's length.
- The implant is not loose or moving.
- You have not had radiation therapy to your head or neck.
- You are not being treated with certain cancer drugs (like Avastin, Revlimid, or methotrexate) and do not have uncontrolled health conditions like severe diabetes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study follows patients with medication-related osteonecrosis of the jaw (a bone condition often caused by certain cancer or osteoporosis medicines) using imaging scans to understand how the bone changes over time. The goal is to better predict outcomes and improve treatment.
This trial tests whether putting a special blood concentrate from your own platelets into the tooth socket after an extraction helps the bone heal better and prevent a serious jaw condition (MRONJ) in people at high risk due to certain medications like bisphosphonates or denosumab.
This trial tests a gel made from polynucleotides and hyaluronic acid (Regenfast) to help heal jaw bone damage caused by osteoporosis or cancer medications (MRONJ). It is for people with early-stage MRONJ who need surgery.
This study looks at your risk of developing a rare jaw bone problem from certain bone-strengthening medications before, during, and after a needed dental procedure. Your participation could help find early warning signs and improve prevention.
This trial compares two surgical techniques for treating medication-related jaw bone problems (MRONJ): one using a special vibrating tool (piezoelectric) and the other using conventional tools. It aims to see which approach leads to better healing and fewer complications.
This Phase 2 trial studies whether a human amniotic membrane dressing can help heal stage II maxillomandibular osteonecrosis of the jaw (MRONJ). It focuses on people who developed MRONJ after certain cancer-related bone treatments and who may need surgery and antibiotics.
Hear when a new Medication Related Osteonecrosis of the Jaw trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.