Timing of tranexamic acid to reduce bleeding and seizures after heart surgery
Part of Brain & nervous system clinical trials.
This trial tests whether giving tranexamic acid at different times during heart surgery can reduce blood loss and the risk of seizures. It may help patients who need certain types of heart surgery with a heart-lung machine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are having heart surgery (like bypass, valve repair/replacement, or aorta replacement) with a heart-lung machine
- You are willing to provide written consent
- You are not allergic to tranexamic acid
- You do not have certain risk factors for bleeding (such as emergency surgery, a bleeding disorder, active infection in the heart, low platelets, or low hemoglobin)
- You do not have severe kidney disease (estimated filtration rate below 30) or need dialysis
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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