Comparing medications to reduce bleeding in heart surgery
Treatments studied
Part of Blood & lymphatic, Heart & circulation clinical trials.
This trial tests two medicines—ACT (a blood thinner) and tranexamic acid (a medicine to reduce bleeding)—to see which is better at controlling bleeding during heart surgery. It is for adults having planned heart surgery with a heart-lung machine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are scheduled for heart surgery that uses a heart-lung machine.
- You are not pregnant.
- Your surgery is not an emergency.
- You do not have a weakened immune system, end-stage kidney disease, or serious liver disease.
- Your surgery is not on the aorta, and you are not in critical condition.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways of giving a medicine called tranexamic acid — as a pill or through an IV — to see which works better at reducing bleeding during heart bypass surgery. If you are having heart surgery without a heart-lung machine, this trial may help you recover with less bleeding.
This study tests a quick bedside measurement of how well the drug tranexamic acid works to prevent bleeding during heart surgery. It may help doctors give the right dose to reduce blood loss.
This study compares different doses of tranexamic acid, a medicine that reduces bleeding, in patients having planned heart surgery with a heart-lung machine. It aims to find the best dose to prevent blood loss.
This trial tests whether giving tranexamic acid through an IV during surgery can reduce bleeding in patients with high-risk conditions like obesity, heart problems, diabetes, or blood clotting issues. It may help make surgery safer for you.
This trial studies whether giving tranexamic acid (TXA) based on patient needs during heart surgery works better than a one-size-fits-all approach. It may help reduce bleeding during surgery, while monitoring for clotting-related side effects.
This trial tests whether a medicine called tranexamic acid, given during surgery to remove part of the prostate, can reduce bleeding. If you are scheduled for this type of prostate surgery, this treatment might help make the procedure safer and improve recovery.
Hear when a new Cardiopulmonary Bypass trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.