Studying atrial fibrillation with mitral regurgitation
Part of Heart & circulation clinical trials.
This trial tests a treatment for people with atrial fibrillation who also have a leaky mitral valve. It aims to see if treating both conditions together can improve symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have atrial fibrillation that comes and goes, and you've had it for less than 5 years.
- You have moderate to severe mitral regurgitation (a leaky heart valve) but your heart's pumping strength is normal.
- You are willing to sign a consent form and come for follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a procedure that combines two treatments for people with atrial fibrillation and a leaky mitral valve that causes symptoms. The procedure aims to fix the valve leak and restore normal heart rhythm, which may improve quality of life and reduce symptoms.
This study tests whether a catheter ablation procedure (a way to fix abnormal heart rhythms) can help people who have both constant atrial fibrillation and severe mitral regurgitation (a leaky heart valve). It is for people whose heart valve leak is caused by the rhythm problem, not by valve damage.
This study looks for hidden (subclinical) atrial fibrillation in people with significant primary mitral regurgitation who have no symptoms or only mild symptoms. Researchers want to see if this heart-rhythm issue occurs without being noticed.
This trial tests a minimally invasive procedure (transcatheter edge-to-edge repair) to fix a leaky mitral valve caused by an enlarged atrium, not by heart muscle damage. It might be an option if your mitral regurgitation is related to atrial issues and your heart's pumping strength is normal.
This study is for people with atrial fibrillation who are planning to have a catheter ablation procedure. It will look at how well the heart works after the procedure and how to prevent future events.
This study tests whether catheter ablation (a procedure to correct irregular heartbeats) helps people with atrial fibrillation who have already had a successful MitraClip repair for a leaky mitral valve. It aims to see if the ablation improves heart rhythm and quality of life.
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