Heart valve repair with ablation for atrial fibrillation and mitral regurgitation
Part of Heart & circulation clinical trials.
This study tests a procedure that combines two treatments: fixing a leaky heart valve (mitral regurgitation) and treating an irregular heartbeat (atrial fibrillation) at the same time. It aims to improve symptoms and heart function in people with both conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- Your heart's pumping strength must be normal or nearly normal (at least 50%).
- You must have a severe leak in your mitral valve (grade 3+ or 4+).
- Your valve must have a shape that allows for the repair procedure.
- Your heart rate must be controlled (under 80 beats per minute at rest, under 110 during exercise).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a minimally invasive procedure (transcatheter edge-to-edge repair) to fix a leaky mitral valve caused by an enlarged atrium, not by heart muscle damage. It might be an option if your mitral regurgitation is related to atrial issues and your heart's pumping strength is normal.
This study tests whether a procedure called catheter ablation, which uses heat or cold to fix irregular heartbeats, is safe and effective for people who have atrial fibrillation and have recently had a mitral valve repair. If you qualify, it might help restore a normal heart rhythm and improve your symptoms.
This study tests whether a catheter ablation procedure (a way to fix abnormal heart rhythms) can help people who have both constant atrial fibrillation and severe mitral regurgitation (a leaky heart valve). It is for people whose heart valve leak is caused by the rhythm problem, not by valve damage.
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