Clinical trials
Atrial Functional Mitral Regurgitation clinical trials
Below are recruiting atrial functional mitral regurgitation clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06823700Recruiting
Study of SQ-Kyrin device for leaky mitral valve from heart failure
This trial tests a new device (SQ-Kyrin) to fix a leaky mitral valve without open-heart surgery. It is for people with heart failure whose valve leak causes symptoms, and who are not good candidates for traditional surgery.
Valladolid, ValladolidAges 18 years+ - NCT07096219Enrolling by invitation
Catheter Ablation for Leaky Mitral Valve in Persistent Atrial Fibrillation
This trial tests if catheter ablation—a procedure to fix heart rhythm—can help people with a leaky mitral valve that is caused by atrial fibrillation (functional mitral regurgitation). If you have persistent atrial fibrillation and moderate leaky valve, you may benefit from this treatment.
Guangzhou, GuangdongAges 18–75 - NCT06467110Enrolling by invitation
Study of SQ-Kyrin TMVr System for leaky mitral valve
This trial tests a new device called the SQ-Kyrin TMVr System to treat severe mitral regurgitation (a leaky heart valve) in people who are not good candidates for traditional open-heart surgery. The goal is to repair the valve without major surgery, using a catheter-based approach.
Shenyang, LiaoningAges 18 years+ - NCT07741383Recruiting
Combined procedure for severe mitral regurgitation and atrial fibrillation
This study tests whether combining a valve repair procedure with a heart rhythm reset procedure is safe and effective for people with severe mitral regurgitation and atrial fibrillation. It may help improve heart function and reduce symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT03975998Recruiting
Early mitral valve repair versus watchful waiting
This trial compares doing mitral valve repair early with closely monitoring symptoms instead, for people who have severe leakage but feel well. It may help determine whether early surgery prevents future heart problems without causing unnecessary risk.
AmsterdamAges 18–75 - NCT05610566Recruiting
HighLife valve replacement for severe leaking mitral valve
This trial studies a new catheter-based valve replacement system for people with moderate to severe, or severe, mitral valve regurgitation (a leaky mitral valve). It aims to check whether the procedure is safe and can improve heart function compared with expected care.
Suzhou, JiangsuAges 18 years+ - NCT05655897Recruiting
Clips for leaky mitral valve in high-surgery-risk heart patients
This trial studies whether a device called GeminiOne can safely and effectively repair a leaky mitral valve using a catheter-based “clip” technique. It may help patients who have moderate-to-severe or severe valve leakage but are considered too high-risk for open surgery.
Suzhou, JiangsuAges 18 years+ - NCT05920824Recruiting
Testing treatment for leaking mitral and tricuspid valves
This trial studies people with atrial fibrillation and moderate-to-severe leakiness in the mitral and tricuspid valves in the heart. It likely aims to improve symptoms and heart function by better addressing how these valve leaks happen.
LondonAges 18 years+ - NCT06630936Recruiting
Studying atrial fibrillation with mitral regurgitation
This trial tests a treatment for people with atrial fibrillation who also have a leaky mitral valve. It aims to see if treating both conditions together can improve symptoms.
Hangzhou, ZhejiangAges 18–80 - NCT06883864Recruiting
Ablation for leaky valve with constant atrial fibrillation
This study tests whether a catheter ablation procedure (a way to fix abnormal heart rhythms) can help people who have both constant atrial fibrillation and severe mitral regurgitation (a leaky heart valve). It is for people whose heart valve leak is caused by the rhythm problem, not by valve damage.
Hefei, AnhuiAges 18–80 - NCT06911099Recruiting
Studying mitral valve repair for atrial regurgitation
This trial tests a minimally invasive procedure (transcatheter edge-to-edge repair) to fix a leaky mitral valve caused by an enlarged atrium, not by heart muscle damage. It might be an option if your mitral regurgitation is related to atrial issues and your heart's pumping strength is normal.
The Bronx, New YorkAges 18 years+ - NCT07131631Recruiting
MitraClip for leaky heart valve in heart failure patients
This trial tests if the MitraClip device helps people with heart failure and a leaky mitral valve. It uses a special MRI to check how the heart responds to treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT05305612Enrolling by invitationPhase 4
Blood thinner timing during heart procedures to protect against clots
This study compares the best way to give blood thinners around certain heart procedures (TEER or left atrial appendage closure). It aims to lower the risk of dangerous clots and bleeding during and after the procedure.
GdanskAges 18 years+ - NCT06805253Recruiting
Heart recovery after surgery for leaky aortic valve
This trial studies how well the heart's main pumping chamber (left ventricle) recovers after surgery to fix a leaky aortic valve. It is for people who also have a leaky mitral valve and an enlarged left ventricle, and who are having their first planned valve surgery.
MoscowAges 18 years+ - NCT03958773Enrolling by invitation
Transcatheter treatment for severe leaking mitral valve
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
KaunasAges 18 years+ - NCT07482020RecruitingPhase 2
SGLT2 inhibitor for atrial fibrillation, high blood pressure, and high blood sugar
This study tests whether a medication called an SGLT2 inhibitor (a type of diabetes drug) can improve the function of the upper left heart chamber in people who have paroxysmal atrial fibrillation, high blood pressure, and abnormal blood sugar levels. If you qualify, the trial may help your heart work better and reduce your risk of stroke.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06951672Recruiting
Testing a new mitral valve repair device
This trial tests a new device called AMEND™ that is placed through a vein in the leg to repair a leaky mitral valve without open-heart surgery. It is for people with significant mitral regurgitation who are at high risk for surgery.
Phoenix, ArizonaAges 21 years+ - NCT06648577Recruiting
3D ultrasound heart muscle wave measurements
This study uses 3D ultrasound to measure mechanical waves in the heart muscle of people with different severities of mitral regurgitation (a leaky heart valve). It aims to better understand how the heart adapts to the leak, which could help guide treatment decisions.
Paris, ParisAges 18 years+ - NCT05040074Recruiting
Transcatheter repair for leaking mitral valve in high-risk patients
This trial studies a minimally invasive device meant to fix a badly leaking mitral valve (mitral regurgitation) without open-heart surgery. It may be an option if you’re considered too high-risk for standard surgery and your heart anatomy fits the device.
Shenyang, LiaoningAges 18 years+ - NCT05194423Recruiting
LuX-Valve procedure for severe leaking tricuspid valve
This trial tests a minimally invasive procedure (LuX-Valve placed through a neck vein) to treat severe leaking of the tricuspid valve. It may help people who are too high-risk for open-heart tricuspid surgery.
Beijing, Beijing MunicipalityAges 50 years+
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Common questions
- Are there clinical trials for atrial functional mitral regurgitation?
- Yes. Clin2 currently lists 22 recruiting atrial functional mitral regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial functional mitral regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial functional mitral regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.