Ablation for leaky valve with constant atrial fibrillation
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a catheter ablation procedure (a way to fix abnormal heart rhythms) can help people who have both constant atrial fibrillation and severe mitral regurgitation (a leaky heart valve). It is for people whose heart valve leak is caused by the rhythm problem, not by valve damage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have severe mitral regurgitation (a leaky heart valve) that is caused by your heart's rhythm problem (atrial fibrillation), not by a damaged valve itself.
- You need to have constant (persistent) atrial fibrillation that does not come and go.
- Your heart's pumping strength (ejection fraction) should be normal (50% or better).
- You must not have had a heart ablation or any mitral valve surgery in the past.
- You should be between 18 and 80 years old.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a procedure called catheter ablation, which uses heat or cold to fix irregular heartbeats, is safe and effective for people who have atrial fibrillation and have recently had a mitral valve repair. If you qualify, it might help restore a normal heart rhythm and improve your symptoms.
This study tests a procedure that combines two treatments: fixing a leaky heart valve (mitral regurgitation) and treating an irregular heartbeat (atrial fibrillation) at the same time. It aims to improve symptoms and heart function in people with both conditions.
This study is for people with atrial fibrillation who are planning to have a catheter ablation procedure. It will look at how well the heart works after the procedure and how to prevent future events.
This study tests a new combination treatment approach for people with long-standing persistent atrial fibrillation (a type of irregular heartbeat that lasts for years). It aims to see if this approach can help improve symptoms and restore a more normal heart rhythm.
This trial tests whether using a special heart-mapping device during ablation (a procedure to fix irregular heartbeats) can improve outcomes for people with persistent atrial fibrillation and an enlarged left heart chamber.
This study compares two types of ablation (a procedure that uses energy to fix irregular heartbeats) for people with persistent atrial fibrillation. It tests whether adding extra treatment to the back of the heart's left upper chamber helps improve outcomes compared to standard treatment alone.
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