Ablation for leaky valve with constant atrial fibrillation
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a catheter ablation procedure (a way to fix abnormal heart rhythms) can help people who have both constant atrial fibrillation and severe mitral regurgitation (a leaky heart valve). It is for people whose heart valve leak is caused by the rhythm problem, not by valve damage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have severe mitral regurgitation (a leaky heart valve) that is caused by your heart's rhythm problem (atrial fibrillation), not by a damaged valve itself.
- You need to have constant (persistent) atrial fibrillation that does not come and go.
- Your heart's pumping strength (ejection fraction) should be normal (50% or better).
- You must not have had a heart ablation or any mitral valve surgery in the past.
- You should be between 18 and 80 years old.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether catheter ablation (a procedure to correct irregular heartbeats) helps people with atrial fibrillation who have already had a successful MitraClip repair for a leaky mitral valve. It aims to see if the ablation improves heart rhythm and quality of life.
This trial tests a procedure that combines two treatments for people with atrial fibrillation and a leaky mitral valve that causes symptoms. The procedure aims to fix the valve leak and restore normal heart rhythm, which may improve quality of life and reduce symptoms.
This trial tests a treatment for people with atrial fibrillation who also have a leaky mitral valve. It aims to see if treating both conditions together can improve symptoms.
This study is for people with atrial fibrillation who are planning to have a catheter ablation procedure. It will look at how well the heart works after the procedure and how to prevent future events.
This trial tests whether using a special heart-mapping device during ablation (a procedure to fix irregular heartbeats) can improve outcomes for people with persistent atrial fibrillation and an enlarged left heart chamber.
This trial tests two different ablation techniques to treat a type of irregular heartbeat that doesn't go away on its own. It aims to find which approach works better and is safer.
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