Prednisone for stubborn restless legs: a pilot study
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests whether the steroid prednisone can help people whose Restless Legs Syndrome has stopped responding to usual treatments. If you have tried first-line RLS medications without success and your symptoms are still severe, this study may offer a new option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Restless Legs Syndrome that does not get better with standard medications.
- Your RLS symptoms are moderate to severe (score above 15 on the RLS rating scale).
- You are an outpatient (not in the hospital) and can read and communicate in English.
- You are not pregnant and do not have iron-deficiency anemia.
- You do not have diabetes, uncontrolled high blood pressure, or a history of serious mental illness.
- You have never had a bad reaction to steroids (like prednisone).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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