Device therapy for restless legs syndrome with medication-related worsening
Part of Brain & nervous system, Mental health clinical trials.
This study tests a wearable device that applies gentle electrical stimulation to the legs to reduce nighttime leg movements and improve sleep. It is for people with Restless Legs Syndrome whose symptoms have gotten worse after long-term use of dopamine medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have been diagnosed with Restless Legs Syndrome (RLS) by a doctor using standard criteria.
- Your RLS symptoms are moderate to severe (score of 15 or more on a standard RLS rating scale).
- Your RLS symptoms have worsened or become harder to control after long-term use of a dopamine medication (this is called augmentation).
- You are currently taking a stable dose of a dopamine agonist (like ropinirole or pramipexole) and agree not to change it during the study.
- On at least 3 nights per week in the past month, you woke up at night with RLS symptoms that made it hard to fall back asleep.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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