Combination therapy for advanced liver cancer after standard treatment fails
Part of Cancer clinical trials.
This trial tests a triple combination of liver-directed chemotherapy (HAIC) plus immunotherapy (PD-1 inhibitor) and targeted therapy (Lenvatinib) for people with advanced liver cancer that has spread into the portal vein and who have already tried and failed standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with liver cancer (HCC) by imaging, biopsy, or cell sample.
- Your cancer is advanced (BCLC stage C) and has spread into the main blood vessel of the liver (portal vein tumor thrombus).
- You have already tried and failed at least one standard systemic treatment for liver cancer.
- You must have at least one measurable tumor in the liver that can be repeatedly checked.
- Your liver function must be fairly good (Child-Pugh class A or B).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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