Testing a PET scan for aldosterone and cortisol condition
Part of Hormones & metabolism clinical trials.
This trial tests whether a special PET/CT scan (68Ga-Pentixafor) can accurately identify the subtype of primary aldosteronism in people who also have excess cortisol. It may help determine if surgery is the right treatment for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with primary aldosteronism (a condition causing high blood pressure from too much aldosterone).
- You also have autonomous cortisol secretion (too much cortisol, often seen after a 1 mg dexamethasone suppression test).
- You are willing to have surgery to remove the affected adrenal gland.
- Your adrenal CT or MRI scan shows a nodule (lump) that is at least 1 cm in size.
- You are not under 35 with low potassium, a large nodule, and very high aldosterone levels (which would allow bypassing a more invasive test).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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