BCMA-GPRC5D CAR-T cells for relapsed multiple myeloma
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests a new kind of immunotherapy that uses your own immune cells, called CAR-T cells, to target two specific markers (BCMA and GPRC5D) found on myeloma cells. It's for people whose multiple myeloma has come back or stopped responding to earlier treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- Your myeloma has returned or not improved after treatments like bortezomib or lenalidomide.
- You have measurable signs of myeloma, such as M protein in your blood or urine, abnormal free light chains, or a tumor that can be seen.
- Your myeloma cells have been tested and are positive for the markers BCMA and GPRC5D.
- You have not had chemotherapy or antibody drugs for at least 2–4 weeks before starting this trial.
- You are generally healthy enough to donate cells by apheresis (a blood collection procedure) and have a life expectancy of at least 12 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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