Gut Bacteria and Blood Substances in Stiff Heart Failure
Part of Digestive system, Heart & circulation clinical trials.
This study looks at how bacteria in your gut and certain substances in your blood relate to a type of heart failure called HFpEF (where the heart is stiff and doesn't relax well). It may help doctors understand the condition better and find new ways to treat it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have symptoms of heart failure, like shortness of breath or tiredness, and your heart function is rated as NYHA class II–IV (moderate to severe).
- Your heart's pumping strength (ejection fraction) is 50% or higher, and it has never been lower than 50% in the past.
- A blood test shows a high BNP (over 35) or NT-proBNP (over 125) level.
- You have at least one sign of heart muscle thickening or stiffness on an ultrasound or echocardiogram.
- You do not have moderate to severe chronic kidney disease (stage 2–4).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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