Heart failure study with preserved pumping function
Part of Heart & circulation clinical trials.
This study looks at how the heart muscle works in people with a type of heart failure where the heart pumps normally but doesn't fill properly. It aims to understand the cause better, which could lead to new treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 30 years or older.
- Your heart pumps at least half the blood out (ejection fraction of 50% or higher).
- You have symptoms like shortness of breath, fatigue, or fluid buildup.
- Your doctor has confirmed heart failure with preserved ejection fraction (HFpEF) based on specific tests or past hospital stays.
- You can safely have a heart biopsy and blood drawn from a vein in your neck.
- You are not taking blood thinners that can't be stopped, or you can stop them safely for the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at a type of heart failure where the heart pumps normally but is too stiff to fill properly. It aims to better understand and classify this condition, which may help guide future treatments.
This study is for people with a type of heart failure called HFpEF, where the heart pumps normally but doesn't relax well. It aims to better understand heart failure through advanced testing, and it includes people who are newly diagnosed or have had a recent hospitalization.
This Phase 2 study tests how matching heart “filling pressure” and heart muscle “energy use” may improve understanding or treatment of HFpEF, a type of heart failure with preserved pumping strength. You may be asked to have heart scans/tests and follow a study plan if your symptoms and test results fit.
This study combines electronic health record data and detailed heart testing to better understand different heart failure types and what treatments may work best for each. It mainly enrolls people with known heart failure, and also some people without heart failure for comparison.
This trial tests whether a structured exercise training program can improve symptoms and quality of life in people with heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but is too stiff to fill properly. Participants will receive exercise training alongside their usual heart failure medications.
This study tests a new drug called finerenone to see if it can improve heart function in people with a type of heart failure where the heart pumps normally but is stiff. It may help reduce symptoms and improve quality of life.
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