Heart failure study with preserved pumping function
Part of Heart & circulation clinical trials.
This study looks at how the heart muscle works in people with a type of heart failure where the heart pumps normally but doesn't fill properly. It aims to understand the cause better, which could lead to new treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 30 years or older.
- Your heart pumps at least half the blood out (ejection fraction of 50% or higher).
- You have symptoms like shortness of breath, fatigue, or fluid buildup.
- Your doctor has confirmed heart failure with preserved ejection fraction (HFpEF) based on specific tests or past hospital stays.
- You can safely have a heart biopsy and blood drawn from a vein in your neck.
- You are not taking blood thinners that can't be stopped, or you can stop them safely for the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study is testing better ways to understand and manage heart failure where the heart pumps normally but still doesn't work as well as it should. It looks at people with symptoms like shortness of breath and fatigue, using blood tests and heart imaging to check eligibility.
This study is for people with a type of heart failure called HFpEF, where the heart pumps normally but doesn't relax well. It aims to better understand heart failure through advanced testing, and it includes people who are newly diagnosed or have had a recent hospitalization.
This study looks at different types of heart failure with preserved ejection fraction (a form of heart failure where the heart pumps normally but doesn't fill properly). Researchers will use past medical records and possibly a special exercise test to better understand these types and how to treat them.
This Phase 2 study tests how matching heart “filling pressure” and heart muscle “energy use” may improve understanding or treatment of HFpEF, a type of heart failure with preserved pumping strength. You may be asked to have heart scans/tests and follow a study plan if your symptoms and test results fit.
This study combines electronic health record data and detailed heart testing to better understand different heart failure types and what treatments may work best for each. It mainly enrolls people with known heart failure, and also some people without heart failure for comparison.
This trial uses special tests to see if you have a type of heart failure where the heart pumps well but doesn't relax properly (HFpEF). It's for people who feel short of breath but haven't been diagnosed with this condition yet.
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