Clin2
NCT06648460Possibly a fitNot yet recruiting

How depression affects choices and effort

DepressionAnhedonia

Part of Brain & nervous system clinical trials.

This study looks at how people with and without depression make decisions about how much effort to put into tasks. It may help understand why depression can make everyday tasks feel harder.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
90 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are between 18 and 65 years old.
  • You are able-bodied and fluent in English.
  • You can give informed consent and understand the study.
  • If you have depression, you must have a diagnosis of major depression and score above 5 on a depression questionnaire.
  • You are not pregnant, have a BMI under 35, and are not taking antipsychotic medications.
  • If you are in the control group, you must not have any other psychiatric diagnosis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04099056Recruiting
Brain scanning and stimulation to study decision-making

This trial uses brain scans and noninvasive brain stimulation to study how people make decisions. It may help researchers understand brain signals involved in choices and potentially improve future treatments.

Atlanta, Georgia
NCT06075771Recruiting· Phase 4
Testing a Parkinson's drug for depression-related loss of interest

This trial tests whether a medication used for Parkinson's disease (carbidopa-levodopa) can help people with major depression who have lost interest or pleasure in things. It is for adults who have not been helped enough by other treatments and have signs of inflammation.

Atlanta, Georgia
NCT05396989Not yet recruiting
How depression affects thinking and memory

This study looks at how depression affects thinking and memory. It may help find better ways to support people with depression.

Changsha, Hunan
NCT07801079Not yet recruiting
Mood and decision-making study across mental health conditions

This study uses a smartphone app to track how your mood and thinking affect your decisions in daily life. It aims to understand mental health symptoms better, which could help improve future treatments.

Bethesda, Maryland
NCT07263321Recruiting
Depression treatment choice in general practice

This study helps people with moderate depression decide between medication and therapy. Your doctor will work with you to pick the best option.

Aalborg
NCT06361095Recruiting· Early Phase 1
Brain training for depression: attention bias modification trial

This trial tests a computer-based brain training program designed to change how you pay attention to emotional information. It may help reduce depression symptoms by training your brain to focus less on negative cues.

Austin, Texas

Hear when a new Depression trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.