Clin2
NCT06649422Possibly a fitNot yet recruiting

Lower chemo dose plus blinatumomab for new B-ALL

Leukemia, Lymphocytic, Acute, Adult

Treatments studied

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a lower dose of chemotherapy followed by 14 days of blinatumomab for adults newly diagnosed with a type of leukemia called B-ALL. The goal is to see if this approach works well and reduces side effects.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
36 people
Ages
15 years to 65 years
Study type
Observational

Who can take part

  • You are between 15 and 65 years old.
  • You have been newly diagnosed with Philadelphia chromosome-negative B-ALL and have not yet had any treatment for it.
  • Your general health status allows you to carry out daily activities (ECOG score 0–2).
  • Your liver and kidney function, heart function, and certain blood tests are within acceptable ranges.
  • You are not pregnant, and you agree to use effective birth control if needed.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06742515Recruiting· Phase 2
Blinatumomab with lower-dose chemo for B-ALL

This trial tests a combination of a targeted drug (blinatumomab) with a lower dose of standard chemotherapy for adults newly diagnosed with a certain type of B-cell acute lymphoblastic leukemia. The goal is to see if this approach is effective and causes fewer side effects than full-dose chemotherapy.

Hangzhou, Zhejiang
NCT06930105Not yet recruiting· Phase 2
Less intense chemo plus blinatumomab before stem cell transplant for B-ALL

This trial tests a combination of low-intensity chemotherapy and a short course of blinatumomab (a targeted immunotherapy) in adults with a certain type of acute leukemia. The goal is to see if this approach helps prepare patients for a stem cell transplant with fewer side effects.

NCT06882057Recruiting· Phase 2/Phase 3
Treatment for newly diagnosed low-risk pediatric B-ALL

This trial tests a treatment plan for children newly diagnosed with low-risk B-cell ALL. It aims to improve outcomes while reducing side effects.

Hefei, Anhui
NCT06504186Not yet recruiting
Blinatumomab for low-level relapse after stem cell transplant

This trial tests a drug called blinatumomab for people with B-ALL whose leukemia has come back at a very low level (detected only by sensitive testing) after a stem cell transplant. The goal is to see if blinatumomab can clear these remaining leukemia cells and prevent a full relapse.

NCT07443592Not yet recruiting
Treatment for adults up to 65 with newly diagnosed ALL

This trial tests a treatment plan for adults aged 18 to 65 who have just been diagnosed with a type of acute lymphoblastic leukemia (ALL) that does not have the Philadelphia chromosome (Ph-negative). The goal is to see how well this therapy works and how safe it is.

A Coruña
NCT04746209Recruiting· Phase 2
Blinatumomab after transplant for high-risk B-ALL patients

This trial tests blinatumomab, an immune therapy, in young people with B-cell acute lymphoblastic leukemia (B-ALL) after their transplant or when they are getting ready for transplant. The goal is to lower the chance of the leukemia coming back by targeting remaining leukemia cells.

Milwaukee, Wisconsin

Hear when a new Leukemia, Lymphocytic, Acute, Adult trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.