Desmoglein-3 antibodies in oral lichen planus
Part of Mouth & dental, Skin clinical trials.
This study looks at a protein called desmoglein-3, which may be linked to oral lichen planus, a condition that causes painful sores in the mouth. The goal is to see if levels of this protein relate to how severe the condition is, which could help guide future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of oral lichen planus (a chronic inflammatory condition of the mouth).
- Your oral lichen planus is the painful type, with red areas or shallow sores, and has been confirmed by a biopsy (a small tissue sample taken from your mouth).
- You are not currently taking certain medications (like steroids, antimalarials, or retinoids) that might affect the condition, or you have stopped them at least 2 weeks before the study (for topical treatments) or 4 weeks before (for oral/systemic treatments).
- You do not have serious health problems such as active infections, cancer, diabetes, high blood pressure, or significant heart, liver, or kidney disease.
- You are not pregnant or breastfeeding.
- You are able to provide consent and are not part of a vulnerable group (such as prisoners or those with mental disabilities).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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