Thyroid medication for mildly high TSH in early pregnancy
Treatments studied
Part of Hormones & metabolism clinical trials.
This study tests whether the thyroid medication levothyroxine can help women with a mildly high TSH level (between 2.5 and the upper limit of normal) during early pregnancy. It is for women who do not have thyroid antibodies and are otherwise healthy, to see if treatment improves pregnancy outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 45 years old and pregnant with a single baby (no twins).
- You became pregnant naturally, without help from fertility treatments.
- Your TSH level was checked in the first 8 weeks of pregnancy and was between 2.5 and the upper limit of normal.
- Your free T4 (another thyroid hormone) is normal and you do not have thyroid antibodies (TPOAb-negative).
- You do not have other thyroid diseases, serious health problems (like high blood pressure or diabetes), or take certain medications that affect thyroid tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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