Late stroke treatment with clot removal or medication
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial compares a procedure to remove a large blood clot from the brain (thrombectomy) with standard medical care for people who had a stroke 24 to 72 hours ago but still have some blood flow around the clot. It aims to see if the procedure can help improve recovery even when started later than usual.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You had a stroke caused by a large blood clot in a key artery in your brain (internal carotid or middle cerebral artery).
- A special scan (CTA) shows that you have moderate to good backup blood flow around the clot.
- You can start the procedure (a puncture in the groin) between 24 and 72 hours after your stroke began.
- You were able to do most daily activities before the stroke (score of 0-2 on the modified Rankin Scale).
- Your stroke symptoms are at least moderate (score of 2 or higher on the NIH Stroke Scale).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at patients who had an ischemic stroke (a type of stroke caused by a blood clot) more than 24 hours ago and have a blockage in a large brain artery. It compares outcomes for those who get a procedure to remove the clot versus those who get only medical treatment.
This trial tests whether removing a blood clot from a large brain artery is better than standard medical care for people who have a mild stroke (NIHSS score 2-5) but still have symptoms like trouble speaking, weakness, or confusion. It is for patients who can be treated within 24 hours of their last known well time.
This trial tests if a procedure to remove a large blood clot from the brain (called a thrombectomy) can help people with severe strokes who have a large damaged area. It is for people who can be treated within 24 hours of their stroke starting.
This trial tests whether removing a clot from a large brain artery up to 72 hours after a stroke helps people recover better than standard care. It uses a special computer program on a regular CT scan to decide who might benefit.
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
This trial tests a procedure to remove a large blood clot in the brain (mechanical thrombectomy) for people who have a very large stroke. It aims to see if removing the clot can improve recovery, even for those with severe strokes.
Hear when a new Stroke, Acute trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.