Clot removal for severe strokes in the back of the brain
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a procedure called endovascular therapy (a way to remove the blood clot using a catheter) for people with a severe stroke caused by a large blockage in the back of the brain. The goal is to see if this treatment can improve outcomes compared to standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- Your stroke was caused by a blockage in the basilar artery, which is a major artery at the back of the brain.
- Symptoms started within the last 24 hours.
- You have a large area of brain damage visible on a scan, and your stroke symptoms are serious (NIHSS score of 10 or higher).
- Before the stroke, you were able to care for yourself (no major disability).
- You agree to participate and sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial is testing whether a clot removal procedure, called endovascular thrombectomy, can help people who have a large stroke in the back part of the brain. To be eligible, the stroke must be from a blocked artery in the base of the skull, and the stroke must be severe and recent.
This trial tests endovascular therapy (a procedure to remove a clot through a tube in an artery) versus medical management for people with a severe stroke due to a blockage in the back part of the brain (basilar artery) and a large area of brain damage. The goal is to see if the procedure improves outcomes compared to medication alone.
This trial tests whether using a catheter-based procedure (endovascular treatment) to open the blocked basilar artery can improve recovery in people with a mild to moderate stroke in the back part of the brain. The goal is to see if this treatment is safe and helps patients recover better than standard care.
This trial tests whether putting a small mesh tube (stent) into a blocked artery in the back of the brain can improve recovery after a severe stroke. It is for people who have had a large stroke in this area and can be treated within 24 hours of symptoms starting.
This trial is for people who had a mild stroke and then got worse within 1 to 14 days, due to a blocked artery in the back of the brain. It tests whether a procedure to open the blocked artery can improve outcomes compared to standard care alone.
This trial compares a procedure to remove a blood clot from a brain artery (endovascular therapy) with standard medicines alone, for people who had a large-vessel stroke more than 24 hours ago (up to 30 days). It aims to see if the procedure can still help improve recovery even after this longer time window, especially if symptoms are fluctuating or worsening.
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