Clot removal versus medication for mild stroke with large vessel blockage
Treatments studied
Part of Brain & nervous system, Heart & circulation, Mental health clinical trials.
This trial compares a procedure to remove the blockage (endovascular therapy) with the best medications alone for people who have a mild stroke caused by a large blocked artery in the brain. The goal is to see if the procedure can improve recovery better than medicine alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- Your stroke must have started within the last 24 hours (using 'last known well' time).
- Your stroke must be mild (NIHSS score 2-5) but include at least one symptom like confusion, facial droop, arm/leg weakness, trouble speaking, or neglect.
- Brain scans (CTA, MRA, or DSA) must show a blockage in a major artery in your brain (carotid or middle cerebral artery).
- A special scan (CTP or MR perfusion) must show a large area of brain at risk (at least 50 mL of tissue with delayed blood flow).
- You (or your legal representative) must agree to participate and sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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