Clin2
NCT06672705Possibly a fitRecruiting

Epcoritamab for lymphoma that returns after an organ transplant

Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative DisorderEBV-Related Post-Transplant Lymphoproliferative DisorderRecurrent Monomorphic Post-Transplant Lymphoproliferative DisorderRecurrent Polymorphic Post-Transplant Lymphoproliferative DisorderRefractory Monomorphic Post-Transplant Lymphoproliferative DisorderRefractory Polymorphic Post-Transplant Lymphoproliferative Disorder

Treatments studied

Part of Cancer, Immune system & allergy clinical trials.

This study tests a drug called epcoritamab for people who have a type of lymphoma that developed after an organ transplant and has not responded to standard treatment. The drug aims to help your immune system fight the cancer cells.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
26 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have post-transplant lymphoproliferative disorder (a type of lymphoma that can happen after an organ transplant) that did not respond to a treatment with rituximab or rituximab plus chemotherapy.
  • You must have had a solid organ transplant (such as kidney, liver, heart, lung, pancreas, or intestine).
  • You must have a tumor that is at least 1.5 cm on a scan or cancer cells in your bone marrow.
  • Your overall health should be reasonably good (able to care for yourself, even if you may need some help).
  • You must have adequate kidney, liver, and blood cell function as determined by blood tests.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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