Clin2
NCT06676696Worth exploringRecruiting

Stopping immunosuppression after failed kidney transplant

Renal Failure , ChronicGraft FailureGraft RejectionAllograftRenal Failure Chronic Requiring Dialysis

Part of Kidney & urinary, Women’s health & pregnancy clinical trials.

This study compares what happens when patients with a failed kidney transplant (still in the body) stop their immunosuppressant medicines at 6 months versus continuing them. The goal is to safely prevent your immune system from becoming too sensitive, which can make finding a new donor kidney harder.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
202 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have had at least one kidney transplant that failed and is still in your body for at least 3 months.
  • You are currently on dialysis (hemodialysis or peritoneal dialysis) for less than 6 months.
  • You are taking the immunosuppressant medicines tacrolimus or cyclosporine along with steroids.
  • Your cPRA blood test result is 90% or less.
  • You are not pregnant and, if able to have children, agree to use effective birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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