Clin2
NCT02558452Possibly a fitNot yet recruiting

Registry study of older kidney transplant patients on Advagraf

Graft FailureDeathAcute Rejection of Renal TransplantInfectionsBone DiseasePost Transplant Diabetes MellitusQuality of LifeHLA Antibody Production

Part of Bones, joints & muscles, Infections clinical trials.

This study follows older people who received a kidney transplant and are taking a specific immune-suppressing medicine plan (Advagraf/tacrolimus once daily plus mycophenolate and steroids). It may help researchers understand outcomes in real-world patients who match these medication and immune-risk criteria.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,000 people
Ages
65 years and older
Study type
Observational

Who can take part

  • You are 65 years or older.
  • You had a kidney transplant (and only one kidney transplant, either first or second).
  • You are taking tacrolimus once daily (Advagraf) as your main “triple therapy,” with a trough level at least 5 ng/mL.
  • You also take mycophenolate (MMF at least 1.0 g/day or EC-MPS at least 720 mg/day) plus prednisone (at least 5 mg/day or equivalent).
  • Your donor was blood-type compatible, and your immune risk at transplant was low (PRA 20% or less and no donor-specific antibodies).
  • You have not had certain other treatments or medicines around transplant (like other induction medicines, or sirolimus/everolimus/belatacept/azathioprine within 3 months).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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