Ephedrine for faster muscle relaxant in elderly patients
Part of Pain clinical trials.
This trial tests whether giving a small dose of ephedrine (a medicine that raises blood pressure) can make the muscle relaxant rocuronium work faster in older adults. It aims to help patients 80+ get a breathing tube placed more quickly during surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 80 years old or older.
- You are scheduled for a planned surgery under general anesthesia that requires a breathing tube.
- You have an ASA physical status rating of I, II, or III (generally healthy to mild to moderate health issues).
- You can read and understand Danish.
- You are not allergic to rocuronium or ephedrine.
- You do not have a neuromuscular disease that would affect muscle response testing.
- You are not needing a rapid sequence induction (a crash emergency intubation).
- You do not take beta-blocker medications daily.
- You do not have a known heart rhythm problem like atrial fibrillation or other irregular rhythms.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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