Comparing muscle relaxants in kidney disease patients during surgery
Treatments studied
Part of Kidney & urinary, Lungs & breathing clinical trials.
This trial compares two muscle relaxants, rocuronium and cisatracurium, to see which causes fewer complications in people with chronic kidney disease (not on dialysis) who need general anesthesia. If you have kidney disease and are having surgery that requires a breathing tube, this study may help determine the safer drug for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You have chronic kidney disease (but not end-stage or needing dialysis)
- You are not pregnant
- You are not in prison or jail
- You are having planned (not emergency) surgery that requires general anesthesia with a breathing tube
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug called HRS-9190 against a standard muscle relaxant (cisatracurium) given continuously through an IV during surgery. It aims to see if the new drug works as well and is safe for adults having planned surgery under general anesthesia.
This study compares a new muscle relaxant medication with a standard one to see how well they work for placing a breathing tube and maintaining muscle relaxation during surgery. It aims to find a safer or more effective option for patients undergoing general anesthesia.
This trial investigates whether giving rocuronium (a muscle relaxant) before the main anesthetic can make muscles relax faster and affect heart rate and blood pressure during the start of general anesthesia. It aims to improve safety and smoothness of the process for people having planned surgery with a breathing tube.
This study compares two ways to monitor muscle relaxation during surgery. It looks at how well a nerve monitor on the arm works versus one on the wrist, to help doctors give the right amount of muscle relaxant medicine.
This trial tests whether using a lower dose of rocuronium (a muscle relaxant used during surgery) works safely during spine surgery when doctors are monitoring your nerves. The goal is to keep your nerves working properly during surgery while using less medication.
This trial uses a device called TetraGraph to measure how quickly a muscle relaxant (rocuronium) works and wears off during surgery. It may help doctors better manage anesthesia for patients who need this medicine.
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