Comparing muscle relaxants in kidney disease patients during surgery
Treatments studied
Part of Kidney & urinary, Lungs & breathing clinical trials.
This trial compares two muscle relaxants, rocuronium and cisatracurium, to see which causes fewer complications in people with chronic kidney disease (not on dialysis) who need general anesthesia. If you have kidney disease and are having surgery that requires a breathing tube, this study may help determine the safer drug for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You have chronic kidney disease (but not end-stage or needing dialysis)
- You are not pregnant
- You are not in prison or jail
- You are having planned (not emergency) surgery that requires general anesthesia with a breathing tube
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study compares a new muscle relaxant medication with a standard one to see how well they work for placing a breathing tube and maintaining muscle relaxation during surgery. It aims to find a safer or more effective option for patients undergoing general anesthesia.
This study compares two ways to monitor muscle relaxation during surgery. It looks at how well a nerve monitor on the arm works versus one on the wrist, to help doctors give the right amount of muscle relaxant medicine.
This study tests whether a low dose of a muscle relaxant called rocuronium is safe and effective during spine surgery when doctors are monitoring the nerves. This may help patients who need spine surgery with nerve monitoring.
This trial tests whether a medication that relaxes muscles (called a neuromuscular blocker) improves breathing help during surgery when a type of airway tube is used. It aims to see if it helps patients breathe better while under anesthesia.
This trial uses a device called TetraGraph to measure how quickly a muscle relaxant (rocuronium) works and wears off during surgery. It may help doctors better manage anesthesia for patients who need this medicine.
This trial compares two places on the hand—the thumb base and the pinky base—to see which is better for monitoring muscle relaxation during surgery. Participants will have their muscle response measured with a gentle electrical test (electromyography) while receiving a standard muscle relaxant (rocuronium).
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