Clin2
NCT06684470Possibly a fitRecruiting

Combining a low-FODMAP diet with medication for IBS-D

IBS - Irritable Bowel SyndromeDiarrhea

Treatments studied

Mirtazapine

Part of Digestive system clinical trials.

This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
20 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old
  • You have been diagnosed with IBS with diarrhea (IBS-D)
  • Your IBS symptoms are moderate to severe (score over 175 on a symptom questionnaire)
  • You have not tried a low-FODMAP diet or mirtazapine before (or tried them without benefit)
  • You do not have other digestive conditions like celiac disease, SIBO, IBD, or microscopic colitis
  • You are not pregnant and can follow study procedures

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07543354Not yet recruiting
Low FODMAP Diet and Mobile App for IBS Symptom Relief

This study tests whether a low FODMAP diet (a specific eating plan that limits certain carbohydrates) combined with a mobile app can help relieve irritable bowel syndrome (IBS) symptoms. The researchers will also look at how gut bacteria and brain signals affect your results.

Taipei
NCT07172139Not yet recruiting
Treating IBS-D with brain stimulation, drugs, or probiotics

This trial tests three treatments for diarrhea-predominant irritable bowel syndrome (IBS-D): brain stimulation (TMS), medication, or probiotics. It aims to find which approach works best to reduce pain and improve bowel symptoms.

NCT07238790Not yet recruiting· Early Phase 1
Bacterial therapy for diarrhea-type irritable bowel syndrome

This trial tests a new treatment made from gut bacteria for people with irritable bowel syndrome that causes diarrhea (IBS-D). The treatment may help restore healthy gut bacteria and reduce symptoms.

Redwood City, California
NCT05120752Recruiting· Phase 3
Low FODMAP diet trial for IBS without lactose intolerance

This trial tests whether eating a low-FODMAP diet can reduce IBS symptoms in people who do not have lactose intolerance. It aims to improve moderate-to-severe IBS symptoms by changing what kinds of carbohydrates you eat.

Jette, Brussels Capital
NCT05097872Recruiting
Diet trial for IBS with non-constipation symptoms

This study tests whether a specific diet plan can improve symptoms in people with IBS that is not constipation (IBS-D or IBS-M). If you qualify, you’ll complete symptom questionnaires and follow the study diet for the trial period to see if symptoms improve.

Leuven
NCT07467278Not yet recruiting
Low-FODMAP diet and gut health in irritable bowel syndrome

This trial tests whether a low-FODMAP diet can improve gut barrier function in people with irritable bowel syndrome. If you have IBS and are willing to follow a specific diet for a few weeks, this study may help you manage your symptoms.

Hear when a new Diarrhea trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.