Combined heart procedure for AFib and stroke prevention
Part of Heart & circulation clinical trials.
This trial combines two procedures at once: a pulsed field ablation to treat atrial fibrillation and a device implant to close the left atrial appendage to reduce stroke risk. It is designed for people in Asia who need both treatments and may benefit from having them together.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You need to have atrial fibrillation and a high stroke risk, so your doctor recommends both ablation and the WATCHMAN device.
- You must be 18 or older and able to give informed consent.
- You cannot have had a prior ablation for AFib or any previous stroke or TIA within the last 90 days.
- Your left atrial appendage anatomy must be suitable for the closure device (doctor will check).
- You must not be pregnant, have a life expectancy under 1 year, or be in another conflicting trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial is for people who need both a special heart treatment called pulsed field ablation (FARAPULSE) and a device to close off a small pouch in the heart (WATCHMAN FLX Pro or WATCHMAN FLX) to prevent strokes. The study will see how well both procedures work when done together.
This study tests a combined approach — a catheter ablation to fix the irregular heartbeat (atrial fibrillation) and a device to close the left atrial appendage — in people who recently had a stroke caused by a clot. The goal is to prevent future strokes and reduce the need for long-term blood thinners.
This trial tests a new type of heart procedure called pulsed field ablation to treat an irregular heartbeat (atrial fibrillation) in people who have already had a device placed to close off a part of the heart (left atrial appendage occlusion). The goal is to see if this safer ablation method can help control your heart rhythm.
This trial tests a new type of catheter ablation (using heat to create scar lines in the heart) for people with persistent atrial fibrillation who have a higher risk of stroke or bleeding. It aims to see if this approach can help prevent strokes and reduce the need for long-term blood thinners.
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