Stroke prevention: combined heart procedure for atrial fibrillation
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests a combined approach — a catheter ablation to fix the irregular heartbeat (atrial fibrillation) and a device to close the left atrial appendage — in people who recently had a stroke caused by a clot. The goal is to prevent future strokes and reduce the need for long-term blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a clot-caused stroke that happened 2 to 12 weeks ago, and you are still having mild to moderate symptoms (or have recovered well).
- You have been told you have atrial fibrillation (an irregular heartbeat), either before or after your stroke.
- You have been taking blood thinners (like warfarin, apixaban, rivaroxaban, or edoxaban) for at least 4 weeks.
- Your heart structure is suitable for two procedures: a catheter ablation (pulmonary vein isolation) and a device to close the left atrial appendage.
- You are between 18 and 80 years old, and you do not have any other major health problems like severe heart failure, kidney failure, active cancer, or a history of bleeding in the brain.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study looks at how treating atrial fibrillation (an irregular heartbeat) with a procedure called ablation—which uses heat or cold to fix the heart's electrical signals—might help improve brain function and recovery after a stroke. It aims to see if controlling the heart rhythm can lead to better neurological outcomes.
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