Clin2
NCT06696833Possibly a fitRecruiting

CD19-targeted CAR-T cell therapy for relapsed B-ALL

B-Cell Acute Lymphoblastic Leukemia, Adult

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.

This trial tests a new type of immune cell therapy (CAR-γδT cells) that targets CD19 on leukemia cells. It is for people with B-cell acute lymphoblastic leukemia that has not responded to treatment or has come back.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
18 people
Ages
14 years and older
Study type
Interventional

Who can take part

  • You are 14 years or older.
  • You have B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to treatment.
  • Your leukemia cells have a protein called CD19 (confirmed by a blood or bone marrow test).
  • Your major organs (heart, lungs, liver, kidneys) are working well enough as shown by recent tests.
  • You have not had a CAR-T cell therapy in the last 6 months and do not have active graft-versus-host disease (GVHD).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07277504Not yet recruiting· Early Phase 1
Personalized CAR T-cell therapy for B-cell acute lymphoblastic leukemia

This trial tests a new way to treat B-cell acute lymphoblastic leukemia (B-ALL). The treatment takes your own immune cells, changes them to fight cancer, and then gives them back to you. The goal is to kill leukemia cells and help you go into remission.

Chengdu, Sichuan
NCT07838714Recruiting· Phase 1
Cord blood CAR-T cells for relapsed B-cell leukemia

This trial tests a new type of personalized cell therapy using your own immune cells (called CAR-T cells) that are designed to find and attack leukemia cells that have certain markers (CD19 and CD22). It is for people whose leukemia has returned or not responded to standard treatments.

Shanghai, Shanghai Municipality
NCT06346912Recruiting· Early Phase 1
CAR-T cell therapy for relapsed B-cell blood cancers

This trial tests a special type of immune therapy called CD19-BAFF CAR-T cells for people whose B-cell acute lymphoblastic leukemia or B-cell non-Hodgkin lymphoma has come back or not responded to standard treatment. The therapy uses your own modified immune cells to target and kill cancer cells.

Hangzhou, Zhejiang
NCT07491263Not yet recruiting· Phase 1
CD19 CAR-γδ T cell therapy for relapsed/refractory B-ALL

This trial tests an experimental cell therapy using your own immune cells (gamma-delta T cells) that are engineered to find and kill cancer cells that carry a protein called CD19. It is for people with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to standard treatments.

Fuzhou, Fujian
NCT07008885Recruiting· Phase 1/Phase 2
New CAR-T cell therapy for relapsed/refractory B-ALL

This trial tests a new type of CAR-T cell therapy that is engineered to be more effective against a specific kind of leukemia (B-ALL) that has returned or not responded to treatment. The therapy uses a patient's own immune cells to target and destroy cancer cells.

Beijing, Biotherapeutic Department of Chinese PLA General Hospital
NCT07244406Recruiting· Phase 2
CAR-T cell therapy for relapsed B-ALL

This trial is testing a new CAR-T cell therapy (Senl_B19) for children and young adults with B-cell acute lymphoblastic leukemia (B-ALL) that has returned or not responded to treatment. It targets a protein called CD19 on leukemia cells to help your immune system attack the cancer.

Beijing

Hear when a new B-Cell Acute Lymphoblastic Leukemia, Adult trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.