Immunotherapy before kidney surgery for high-risk kidney cancer
Treatments studied
Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests a combination of two immunotherapy drugs (cemiplimab and fianlimab) given before surgery for high-risk kidney cancer that has not spread. The goal is to see if the drugs can help reduce the risk of the cancer coming back or spreading in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and are scheduled to have surgery to remove your kidney (nephrectomy) for clear cell renal cell carcinoma, a type of kidney cancer.
- Your kidney cancer is considered high risk (meaning there is a high chance it could spread) but has not yet spread to other parts of your body.
- You have not had any prior treatment for kidney cancer, including immunotherapy (medicines that help your immune system fight cancer).
- You are healthy enough to safely wait about 9 weeks before your kidney surgery.
- You must have good organ function, such as normal blood cell counts and kidney/liver function, as shown by blood tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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