Tasimelteon for delayed sleep phase disorder with genetic variant
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests a new sleep medication called tasimelteon compared to a placebo (inactive treatment) for people with a specific sleep disorder linked to a genetic change in the body's internal clock. If you have Delayed Sleep-Wake Phase Disorder and carry the CRY1Δ11 variant, this trial may help improve your sleep timing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You must have a diagnosis of Delayed Sleep-Wake Phase Disorder (a condition where your body's sleep clock is shifted later than normal).
- You must have a specific genetic change called the CRY1Δ11 variant (this affects your internal body clock).
- Your body mass index (BMI) must be between 18 and 40.
- You cannot currently use tobacco products or test positive for drugs of abuse.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if the drug tasimelteon helps children with insomnia sleep better compared to a placebo (a pill with no medicine). It is for children aged 2 to 17 who have been diagnosed with insomnia that is not caused by another medicine.
This trial tests whether a sleep medication called lemborexant can help people with delayed sleep phase syndrome fall asleep earlier. It may improve sleep timing and reduce the impact on daily life.
This trial tests a new medicine, daridorexant, to see if it helps people with insomnia sleep better through the night and feel more alert during the day. The study will use a home device to check your sleep patterns before you join.
This study tests a sleep medication called ramelteon for people with chronic insomnia. If you qualify, you may receive the study drug or a placebo, and researchers will monitor your sleep over several weeks to see if it helps you fall asleep faster and sleep longer.
This study looks at how your body's internal clock works in people with delayed sleep-wake phase disorder, especially those living at high altitudes. It aims to understand the causes of this sleep problem and may help find better treatments.
This trial studies whether timed light exposure can help people who have trouble falling asleep. It aims to improve insomnia symptoms by testing a light-based approach while carefully measuring sleep patterns.
Hear when a new Sleep Wake Disorders trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.