Pacing methods to protect heart function
Part of Heart & circulation clinical trials.
This trial tests two pacing approaches to see which one better prevents weakening of the heart's main pumping chamber. It's for people who need a pacemaker for a slow heart rhythm and are expected to rely on it heavily.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your heart's main pumping chamber is working at least 40% of normal (mild or no weakness).
- You need a pacemaker because your heart's electrical signal is blocked (high-degree AV block) and you'll likely need pacing more than 80% of the time.
- Your doctor expects you to live at least one more year and you agree to follow the study plan.
- You do not already need a defibrillator (ICD) or a special heart resynchronization device (CRT).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two types of “left-side” heart pacing to see which one works better in people with weak heart pumping. It may help guide the best pacing choice for improving heart function and symptoms.
This study uses MRI scans to see how different pacing methods affect your heart's performance. It may help doctors choose the best pacing for you if you need a pacemaker for certain heart block conditions.
This study looks at a heart pacing approach to prevent damage to the heart muscle that can sometimes happen after a pacemaker is placed for atrioventricular (heart rhythm) block. It may help some people avoid worsening heart function over time.
This study compares two pacemaker pacing strategies—left-sided “bundle branch area” pacing versus right-sided ventricular pacing. It aims to see which approach better prevents heart failure getting worse and reduces abnormal timing between heart chambers over time.
This study compares two types of pacemaker pacing methods in people with heart block and normal heart pumping function. It looks at how often short bursts of fast heart rhythm occur in the upper heart chambers, which may help improve long-term heart health.
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
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