Pacing options for AF with low heart function
Part of Heart & circulation clinical trials.
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older with permanent atrial fibrillation (AF) and a weakened heart pump (ejection fraction below 50%)
- You need a pacemaker for a slow heartbeat or are scheduled for AV node ablation, or your doctor has recommended cardiac resynchronization therapy (CRT)
- Your pacemaker is expected to be used more than 40% of the time
- You have been on heart failure medications for at least 3 months
- If you already have a pacemaker or defibrillator, it can be upgraded to a CRT device
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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