Alcohol use disorder study of an oral medication
Part of Brain & nervous system, Mental health clinical trials.
This study tests an experimental medicine called AFA-281, taken by mouth, to see if it's safe and if it helps people drink less. You might join if you have alcohol use disorder and drink quite a lot each week.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between the ages of 21 and 65.
- You must have a diagnosis of moderate or severe alcohol use disorder from the past year.
- You need to drink at least 28 drinks per week (if you're a man) or 21 drinks per week (if you're a woman).
- You must agree to use birth control (like condoms) or be sexually inactive during the study, and not donate sperm for 90 days after treatment.
- You cannot be currently in treatment for alcohol use or have been in treatment in the last 30 days.
- You must not have certain other health conditions, like recent seizures, liver problems, or a history of severe mental illness.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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